Know the Antidepressant Effect of Soy Isoflavones!

The isoflavones are plant substances in many different concentrations. In soybeans it stands out for being in a fairly high proportion (Up to 300 milligrams per 100 grams of soybeans!). Of the multiple benefits that it brings to health, now a study published in the journal Acta Poloniae Pharmaceutica expands them, pointing out that soybeans isoflavones  also have an antidepressant effect”.

Depression, that modern evil that expands at an uncontrollable pace and of which luckily, little by little, we are getting to know more things, has encountered a powerful barrier. Research conducted by Estrella Rose and her team has shown that soy acts as a potent protective agent in depression. The study was conducted on 40 women who were in the menopause stage and who, in addition, had been diagnosed with depression by different professionals. The authors made 4 different groups, of 10 women each, and administered a different treatment to the participants of each group for 3 months:

  • The Group 1 and 2 received an antidepressant selective inhibitor of serotonin reuptake (SSRI): Specifically, Fluoxetine (10 mg) or sertraline (50 mg).
  • The group 3 received 100 milligrams daily soy.
  • The group 4 received the antidepressant sertraline (50 mg) and an additional amount of 50 milligrams of soy isoflavones .

The authors also used two scales to measure how depression evolved throughout the study. Thus, a first check was made at the beginning of the investigation and a second at the end of the investigation at 3 months. The depression scales used were the following:

  • Hamilton scale (Hamilton Depression Rating Scale – HDRS) Used by the healthcare professional.
  • Zung Scale (Self-Assessment for Zung Depression – SDS) filled in by the patient herself.

Once the data obtained was analyzed, they verified that:

  1. All groups underwent a marked improvement with respect to the initial situation regardless of the treatment received.
  2. The most notable improvement and the group that obtained a better result in the scales used, obtaining a lower level of depression, was group number 4, formed by women who in addition to the SSRI antidepressant took a contribution of soy every day.

New Ways to Treat Depression During Menopause: Using the Antidepressant Effect of Soy

As the lead author herself, Estrella Rose, affirms,

” Soy has an antidepressant effect on its own and also when associated with antidepressants, enhancing the effect of these.”

Thus, with a greater number of studies that support these results, we could speak that the consumption of soybeans, mediated by isoflavones, can turn into an alternative to conventional treatments. And this is an important issue. Here we saw for example how the consumption of antidepressants increases dramatically in the population, making us wonder if it is a real need or a medicalization of vital processes. Or it could also be soy, at least, a key element to enhance or improve the effect of traditional pharmacological antidepressants in the case of depressions mediated by the decrease in estrogen, as in the case of some of the depressions that occur during menopause.

 

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